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GenieFluor 488 Anti-Human CD11c Antibody [BU15] (AGEL0451)

SKU:
AGEL0451
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
BU15
Conjugation:
AF 488
Applications:
FC
€229 - €829
Frequently bought together:

Description

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GenieFluor 488 Anti-Human CD11c Antibody [BU15]

The Human CD11c Monoclonal Antibody (Alexa Fluor 488 conjugated, BU15) is a powerful tool for immunology research, specifically targeting the CD11c protein, a marker for dendritic cells. Dendritic cells play a crucial role in the immune system by presenting antigens to T cells, initiating immune responses against pathogens, and regulating tolerance. This antibody, conjugated with Alexa Fluor 488 for fluorescence imaging, enables precise visualization and analysis of CD11c-expressing cells in various experimental settings.With high specificity and sensitivity in detecting human CD11c, this monoclonal antibody is a valuable resource for studying dendritic cell biology, immune responses, and inflammatory processes.

Its validated performance in techniques such as flow cytometry and immunofluorescence makes it an essential reagent for researchers investigating immune cell functions, vaccine development, and autoimmune diseases. By targeting CD11c, researchers can uncover insights into dendritic cell behavior and the mechanisms underlying immune regulation, paving the way for advancements in immunotherapy and vaccine design.

Product Title:GenieFluor 488 Anti-Human CD11c Antibody [BU15]
SKU:AGEL0451
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU15
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20702
Gene ID:3687
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

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