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PE/Cyanine5 Anti-Human CD11a Antibody [R7-1] (AGEL2088)

SKU:
AGEL2088
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€149 - €499

Description

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PE/Cyanine5 Anti-Human CD11a Antibody [R7-1]

The Human CD11a Monoclonal Antibody PE-Cyanine5 Conjugated (R7-1) is an essential tool for researchers studying the CD11a protein, a crucial component of the integrin lymphocyte function-associated antigen 1 (LFA-1). This monoclonal antibody, conjugated with PE-Cyanine5, is specifically designed for flow cytometry applications and offers high sensitivity and specificity in detecting human CD11a.CD11a plays a vital role in mediating immune cell adhesion and activation, making it a key target for investigations in immunology and inflammation research. By using this antibody, researchers can effectively analyze the expression and function of CD11a in various cell types, providing valuable insights into immune responses and inflammatory processes.

The PE-Cyanine5 conjugation of this antibody allows for multiparameter flow cytometry analysis, enabling simultaneous detection of CD11a along with other cell surface markers. Its compatibility with a wide range of flow cytometers further enhances its versatility in immunophenotyping studies and functional assays.Overall, the Human CD11a Monoclonal Antibody PE-Cyanine5 Conjugated (R7-1) is an indispensable tool for researchers aiming to investigate the role of CD11a in immune cell interactions, inflammatory responses, and immune-mediated diseases. Its high performance and specificity make it an ideal choice for precise and reliable flow cytometry experiments in the fields of immunology and beyond.

Product Title:PE/Cyanine5 Anti-Human CD11a Antibody [R7-1]
SKU:AGEL2088
Size:20 Tests, 100 Tests, 200 Tests
Clone No:R7-1
Synonyms:Integrin alpha-L;LFA-1A;CD11A;ITGAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20701
Gene ID:3683
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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