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APC Anti-Human CD11a Antibody [TS1/22.1.1.13] (AGEL0963)

SKU:
AGEL0963
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
TS1/22.1.1.13
Conjugation:
APC
€119 - €389
Frequently bought together:

Description

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APC Anti-Human CD11a Antibody [TS1/22.1.1.13]

The Human CD11a Monoclonal Antibody APC Conjugated (TS1/22.1.1/13) is a powerful tool for research involving CD11a, a cell surface protein that is a key component of the integrin lymphocyte function-associated antigen 1 (LFA-1). This antibody, developed by Assay Genie, is specifically designed for use in flow cytometry applications and is conjugated to allophycocyanin (APC) for enhanced detection and analysis.CD11a plays a crucial role in immune cell adhesion and activation, particularly in processes such as T cell activation and migration. By targeting CD11a, researchers can gain valuable insights into immune cell function, particularly in the context of inflammatory responses, immune surveillance, and host defense mechanisms.

With its high specificity and reactivity with human samples, the Human CD11a Monoclonal Antibody APC Conjugated (TS1/22.1.1/13) is a valuable tool for immunology research, including studies focused on immune cell interactions, inflammatory diseases, and autoimmune conditions. Its use in flow cytometry allows for precise and reliable analysis of CD11a expression on various cell populations, making it an essential reagent for investigations into immune system regulation and dysfunction.

Product Title:APC Anti-Human CD11a Antibody [TS1/22.1.1.13]
SKU:AGEL0963
Size:20 Tests, 100 Tests, 200 Tests
Clone No:TS1/22.1.1.13
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20701
Gene ID:3683
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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