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GenieFluor 647 Anti-Human CD11a Antibody [R7-1] (AGEL2091)

SKU:
AGEL2091
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
€139 - €469
Frequently bought together:

Description

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GenieFluor 647 Anti-Human CD11a Antibody [R7-1]

The Human CD11a Monoclonal Antibody (AF647 Conjugated, R7-1) offered by AssayGenie (AGEL2091) is a cutting-edge tool for research applications involving CD11a, a cell surface glycoprotein. This antibody is specifically designed for use in immunology and cell biology studies focused on the role of CD11a in cell adhesion, migration, and signal transduction processes. CD11a, also known as integrin alpha L, is a crucial component of the Lymphocyte Function-Associated Antigen 1 (LFA-1) heterodimer, which is involved in immune cell interactions and inflammation responses. The AF647 conjugated monoclonal antibody enables precise detection and analysis of CD11a expression in human samples, making it an invaluable asset for investigating immune cell function and interactions in a variety of contexts.

With its high specificity and sensitivity, this antibody is suitable for various immunofluorescence applications, flow cytometry, and immunohistochemistry studies, providing researchers with a reliable tool to advance their understanding of CD11a-mediated processes. Explore the intricate mechanisms of immune cell signaling and adhesion with the Human CD11a Monoclonal Antibody from AssayGenie, empowering your research efforts in immunology and beyond.

Product Title:GenieFluor 647 Anti-Human CD11a Antibody [R7-1]
SKU:AGEL2091
Size:20 Tests, 100 Tests, 200 Tests
Clone No:R7-1
Synonyms:Integrin alpha-L;LFA-1A;CD11A;ITGAL;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20701
Gene ID:3683
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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