GenieFluor 647 Anti-Human CD11a Antibody [R7-1] (AGEL2091)
- SKU:
- AGEL2091
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Applications:
- FC
Frequently bought together:
Description
Product Title: | GenieFluor 647 Anti-Human CD11a Antibody [R7-1] |
SKU: | AGEL2091 |
Size: | 20 Tests, 100 Tests, 200 Tests |
Clone No: | R7-1 |
Synonyms: | Integrin alpha-L;LFA-1A;CD11A;ITGAL; |
Host Species: | Mouse |
Reactivity: | Human |
Application: | FCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21] |
Form: | Liquid |
Conjugation: | Genie Fluor647 |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Spectrum: |
Swissprot: | P20701 |
Gene ID: | 3683 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |