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FITC Anti-Human CD117 Antibody [104D2] (AGEL1777)

SKU:
AGEL1777
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$227 - $851
Frequently bought together:

Description

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FITC Anti-Human CD117 Antibody [104D2]

The Human CD117 Monoclonal Antibody (FITC-conjugated, 104D2) from AssayGenie (AGEL1777) is a cutting-edge tool designed for researchers studying CD117, a cell surface receptor also known as c-kit or stem cell factor receptor. This antibody is specifically engineered for use in flow cytometry applications, providing high specificity and sensitivity for detecting CD117 expression in human samples.CD117, a vital marker for identifying hematopoietic stem cells and various types of cancer cells, plays a crucial role in cell proliferation, differentiation, and survival. By targeting CD117 with this monoclonal antibody, researchers can effectively identify and analyze CD117-expressing cells in both normal and diseased tissues.

This antibody enables precise detection and characterization of CD117-positive cells, making it invaluable for studies in stem cell biology, oncology, and hematopoiesis research.Utilizing the Human CD117 Monoclonal Antibody (FITC-conjugated, 104D2) offers a powerful tool for investigating the role of CD117 in various biological processes and disease pathways. Its exceptional performance and specificity make it a dependable choice for researchers seeking to unravel the complexities of CD117 signaling and function in health and disease.

Product Title:FITC Anti-Human CD117 Antibody [104D2]
SKU:AGEL1777
Size:20 Tests, 100 Tests, 200 Tests
Clone No:104D2
Synonyms:Mast/stem cell growth factor receptor Kit;Kit;SCFR;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;CD117;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P10721
Gene ID:3815
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.

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