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PE Anti-Human CD107a/LAMP-1 Antibody [H4A3] (AGEL1775)

SKU:
AGEL1775
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
$227 - $755
Frequently bought together:

Description

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PE Anti-Human CD107a/LAMP-1 Antibody [H4A3]

The CD107A (LAMP-1) Monoclonal Antibody (PE Conjugated) (H4A3) is a cutting-edge tool for researchers in the field of immunology. This antibody, developed by Assay Genie, is specifically designed for the detection and analysis of CD107A, also known as LAMP-1, a vital cell surface glycoprotein involved in lysosomal function and cell-mediated cytotoxicity.The H4A3 antibody is engineered to bind with high specificity to the CD107A protein in human samples, allowing for precise identification and characterization in a variety of cell types. Its PE conjugation enhances signal detection in flow cytometry and imaging applications, making it an indispensable resource for immunologists investigating immune responses, cytotoxic mechanisms, and cell trafficking.

With its proven reliability and specificity, the CD107A (LAMP-1) Monoclonal Antibody (PE Conjugated) (H4A3) from Assay Genie is a valuable asset for studies exploring immune cell biology, cancer immunotherapy, and infectious disease pathogenesis. Researchers can rely on this antibody to unlock crucial insights into the intricate mechanisms governing immune function and cellular interactions, paving the way for innovative advancements in biomedical research.

Product Title:PE Anti-Human CD107a/LAMP-1 Antibody [H4A3]
SKU:AGEL1775
Size:20 Tests, 100 Tests, 200 Tests
Clone No:H4A3
Synonyms:Lysosome-Associated Membrane Protein 1; LGP-120; LAMP-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11279
Gene ID:3916
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

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