The Human CD10 Monoclonal Antibody (PE-Cyanine5 Conjugated) is a vital tool for researchers studying CD10 expression in human samples. CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is a cell surface enzyme with a role in cell differentiation and maturation. This monoclonal antibody, conjugated with PE-Cyanine5, allows for efficient detection and analysis of CD10 expression using flow cytometry and immunofluorescence techniques.CD10 is commonly used as a marker for identifying and characterizing various cell types, particularly in hematological malignancies and solid tumors. Its expression patterns can provide insights into disease progression, prognosis, and treatment response.
The Human CD10 Monoclonal Antibody is specifically engineered to target CD10 antigen, enabling precise and reliable detection in research settings.With its high specificity and sensitivity, this antibody is an essential tool for investigations in oncology, immunology, and cell biology. By elucidating the role of CD10 in various cellular processes and disease states, researchers can advance their understanding of cancer biology and potentially discover new therapeutic targets. The Human CD10 Monoclonal Antibody is a valuable asset for scientists seeking to unravel the complexities of CD10 expression and function in human tissues.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08473
Gene ID:
4311
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.