The Human CD10 Monoclonal Antibody - Biotin Conjugated (CB-CALLA-AGEL0295) offered by Assay Genie is a cutting-edge tool for research applications involving CD10, a cell surface marker known for its role in cell differentiation and maturation. This monoclonal antibody, meticulously developed with biotin conjugation for enhanced detection capabilities, boasts high specificity and sensitivity in human samples.CD10, also referred to as common acute lymphoblastic leukemia antigen (CALLA), serves as a vital biomarker in various biological processes, particularly in the context of hematopoietic cell development and malignancies. Its expression levels and localization can provide valuable insights into cell lineage determination and pathological conditions, making it an indispensable target in research areas like oncology and developmental biology.
With its superior performance in techniques such as immunohistochemistry and flow cytometry, the Human CD10 Monoclonal Antibody - Biotin Conjugated (CB-CALLA-AGEL0295) enables precise and reliable detection of CD10 expression in a wide range of experimental settings. Researchers focused on understanding cellular differentiation, tumor characterization, and therapeutic targeting will find this antibody instrumental in advancing their investigations and uncovering new discoveries in the field of biomedicine.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P08473
Gene ID:
4311
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.