The Human CD10 Monoclonal Antibody (APC Conjugated) is a vital tool for researchers studying CD10, an important cell surface marker involved in various cellular processes. This monoclonal antibody, labeled with allophycocyanin (APC), demonstrates high specificity and sensitivity when detecting human CD10 in samples, making it a reliable tool for flow cytometry and immunofluorescence studies.CD10, also known as common acute lymphoblastic leukemia antigen (CALLA), is a cell surface enzyme that plays a key role in cell development and differentiation. Its expression pattern is often used to distinguish different cell lineages, making it a valuable marker in hematopoietic and lymphoid studies.
The APC-conjugated CD10 antibody allows for precise identification and analysis of CD10-positive cells in various experimental settings.Researchers in the fields of immunology, hematology, and oncology can benefit from the use of this antibody to explore the role of CD10 in cell maturation, disease progression, and therapeutic responses. By targeting CD10 with this specific monoclonal antibody, researchers can gain insights into the complex mechanisms underlying cellular functions and disease pathologies, ultimately paving the way for novel diagnostic and treatment strategies.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08473
Gene ID:
4311
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.