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Human CCR4-Strep full length protein-synthetic nanodisc (HDFP770)

SKU:
HDFP770
Size:
10μg
Target:
CCR4
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249

Description

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Product Name:Nanodisc Human CCR4-Strep Protein
SKU:HDFP770
Size:10μg
Target:CCR4
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4
Protein Families:GPCR.
Protein Description:Human CCR4-Strep full length protein-synthetic nanodisc
Protein Pathways:Chemokine signaling pathway, Cytokine-cytokine receptor interaction.
Molecular Weight:The human full length CCR4-Strep Protein has a MW of 41.4 kDa

The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine – MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Uniprot ID:P51679
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

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