Human CCR2 full length protein-MNP (HDFP492)
- SKU:
- HDFP492
- Size:
- 50μg
- Target:
- CCR2
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human CCR2 full length protein-MNP |
| SKU: | HDFP492 |
| Size: | 50μg |
| Target: | CCR2 |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R |
| Protein Families: | Druggable Genome, Transmembrane. |
| Protein Description: | Human CCR2 full length protein-MNP |
| Protein Pathways: | Chemokine signaling pathway, Cytokine-cytokine receptor interaction. |
| Molecular Weight: | The human full length CCR2 protein has a MW of 41.9 kDa |
The protein is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3.
| Uniprot ID: | P41597 |
| Formulation & Reconstitution: | Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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