Human CCR2 Full-Length Bioactive Membrane Protein (HDFP011)
- SKU:
- HDFP011
- Product Type:
- Recombinant Protein
- Protein Type:
- Full-Length Bioactive Membrane Protein
- Species:
- Human
- Uniprot:
- P41597
Description
system_update_altDatasheet
| Product name | Human CCR2 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP011 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | CCR2 |
| Uniprot: | P41597 |
| Description: | Human CCR2 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length CCR2 protein has a MW of 41.9 kDa |
| Protein Family: | Druggable Genome, Transmembrane |
| Protein Pathways: | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | CC-CKR-2; CCR-2; CCR2A; CCR2B; CD192; CKR2; CKR2A; CKR2B; CMKBR2; MCP-1-R |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | The protein is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection. This gene is located in the chemokine receptor gene cluster region of chromosome 3. |
| Delivery: | In Stock |
| Usage | Research use only |
Related Products
