Human CARHSP1 Recombinant Protein (RPPB2985)
- SKU:
- RPPB2985
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O95057
Frequently bought together:
Description
| Product Name: | Human CARHSP1 Recombinant Protein |
| Product Code: | RPPB2985 |
| Size: | 10µg |
| Species: | Human |
| Target: | CARHSP1 |
| Synonyms: | Calcium-regulated heat stable protein 1, Calcium-regulated heat-stable protein of 24 kDa, CRHSP-24, CARHSP1, asCSDC1, MGC111446. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CRAHSP1 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSSEPPPPPQ PPTHQASVGL LDTPRSRERS PSPLRGNVVP SPLPTRRTRT FSATVRASQG PVYKGVCKCF CRSKGHGFIT PADGGPDIFL HISDVEGEYV PVEGDEVTYK MCSIPPKNEK LQAVEVVITH LAPGTKHETW SGHVISS |
CRAHSP1 is a serine phosphoprotein initially identified as a physiological substrate for the Ca2+-calmodulin regulated protein phosphatase calcineurin (PP2B). CRAHSP1 interacts with the STYX/dead phosphate protein in developing spermatids and is a paralog of the brain-specific mRNA-binding protein PIPPIN. It is believed to have a common role in calcium-mediated signal transduction resulting from phosphorylation on serine residues.
CRAHSP1 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 167 amino acids (1-147 a.a.) and having a molecular mass of 18kDa. The CRAHSP1 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | DIRAS1: Displays low GTPase activity and exist predominantly in the GTP-bound form. Belongs to the small GTPase superfamily. Di-Ras family.Protein type: G protein, monomeric, di-Ras; G protein; G protein, monomericChromosomal Location of Human Ortholog: 19p13.3Cellular Component: plasma membraneMolecular Function: GTP binding; GTPase activity; mitogen-activated protein kinase bindingBiological Process: positive regulation of MAP kinase activity |
| UniProt Protein Details: | |
| NCBI Summary: | DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004] |
| UniProt Code: | O95057 |
| NCBI GenInfo Identifier: | 62286591 |
| NCBI Gene ID: | 148252 |
| NCBI Accession: | O95057.1 |
| UniProt Secondary Accession: | O95057 |
| UniProt Related Accession: | O95057 |
| Molecular Weight: | 22,329 Da |
| NCBI Full Name: | GTP-binding protein Di-Ras1 |
| NCBI Synonym Full Names: | DIRAS family GTPase 1 |
| NCBI Official Symbol: | DIRAS1�� |
| NCBI Official Synonym Symbols: | RIG; GBTS1; Di-Ras1�� |
| NCBI Protein Information: | GTP-binding protein Di-Ras1 |
| UniProt Protein Name: | GTP-binding protein Di-Ras1 |
| UniProt Synonym Protein Names: | Distinct subgroup of the Ras family member 1; Ras-related inhibitor of cell growth; Rig; Small GTP-binding tumor suppressor 1 |
| Protein Family: | GTP-binding protein |
| UniProt Gene Name: | DIRAS1�� |
| UniProt Entry Name: | DIRA1_HUMAN |
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