Human CAPS Recombinant Protein (RPPB2980)
- SKU:
- RPPB2980
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q13938
Description
| Product Name: | Human CAPS Recombinant Protein |
| Product Code: | RPPB2980 |
| Size: | 20µg |
| Species: | Human |
| Target: | CAPS |
| Synonyms: | Calcyphosin, Calcyphosine, CAPS, CAPS1, MGC126562. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The CAPS solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 2mM DTT and 100mM NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MDAVDATMEK LRAQCLSRGA SGIQGLARFF RQLDRDGSRS LDADEFRQGL AKLGLVLDQA EAEGVCRKWD RNGSGTLDLE EFLRALRPPM SQAREAVIAA AFAKLDRSGD GVVTVDDLRG VYSGRAHPKV RSGEWTEDEV LRRFLDNFDS SEKDGQVTLA EFQDYYSGVS ASMNTDEEFV AMMTSAWQL |
Calcyphosine (CAPS) is a calcium-binding protein containing four EF-hand domains. CAPS protein was originally identified as thyroid protein p24 which is found in a number of epithelium and in some cells of the central nervous system. CAPS may have a role in the regulation of ion transport. In the thyroid follicular cells, CAPS is synthesized and phosphorylated in response to stimulation by thyrotropin and cAMP agonists.
CAPS Human Recombinant fused with a�20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing�209 amino acids (1-189 a.a.) and having a molecular mass of 23.1kDa. The CAPS is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CAPS: Calcium-binding protein. May play a role in cellular signaling events (Potential). |
| UniProt Protein Details: | Protein type:Calcium-binding Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: cytoplasm; vesicle Molecular Function:calcium ion binding |
| NCBI Summary: | This gene encodes a calcium-binding protein, which may play a role in the regulation of ion transport. A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit. Alternative splicing of this gene generates two transcript variants. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13938 |
| NCBI GenInfo Identifier: | 2493439 |
| NCBI Gene ID: | 828 |
| NCBI Accession: | Q13938.1 |
| UniProt Secondary Accession: | Q13938,Q3MJA7, Q8WUZ3, |
| UniProt Related Accession: | Q13938 |
| Molecular Weight: | 17,770 Da |
| NCBI Full Name: | Calcyphosin |
| NCBI Synonym Full Names: | calcyphosine |
| NCBI Official Symbol: | CAPS�� |
| NCBI Official Synonym Symbols: | CAPS1�� |
| NCBI Protein Information: | calcyphosin |
| UniProt Protein Name: | Calcyphosin |
| UniProt Synonym Protein Names: | Calcyphosine |
| Protein Family: | Calcyphosin |
| UniProt Gene Name: | CAPS�� |
