Human CALCR-Strep full length protein-synthetic nanodisc (HDFP760)
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- SKU:
- HDFP760
- Size:
- 10μg
- Target:
- CALCR
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human CALCR-Strep Protein |
| SKU: | HDFP760 |
| Size: | 10μg |
| Target: | CALCR |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | CRT, CT-R, CTR, CTR1 |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human CALCR-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | GPCRDB Class B Secretin-like, G-Protein Coupled Receptors Signaling Pathway. |
| Molecular Weight: | The human full length CALCR-Strep protein has a MW of 55.3kDa |
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
| Uniprot ID: | P30988 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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