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Human C5AR1-Strep full length protein-synthetic nanodisc (HDFP823)

SKU:
HDFP823
Size:
10μg
Target:
C5AR1
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249
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Description

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Product Name:Nanodisc Human C5AR1-Strep Protein
SKU:HDFP823
Size:10μg
Target:C5AR1
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:C5A; C5AR; C5R1; CD88
Protein Families:Druggable Genome, GPCR, Transmembrane.
Protein Description:Human C5AR1-Strep full length protein-synthetic nanodisc
Protein Pathways:Complement and coagulation cascades, Neuroactive ligand-receptor interaction.
Molecular Weight:The human full length C5AR1-Strep protein has a MW of 39.3 kDa

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production

Uniprot ID:P21730
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

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