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Human BCL7C Recombinant Protein (RPPB5853)

SKU:
RPPB5853
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q8WUZ0
€309
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Description

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Product Name:Human BCL7C Recombinant Protein
Product Code:RPPB5853
Size:10µg
Species:Human
Target:BCL7C
Synonyms:B-Cell CLL/Lymphoma 7C, B-Cell CLL/Lymphoma 7 Protein Family Member C, BCL7C.
Source:Escherichia Coli
Physical Appearance:Sterile filtered colorless solution.
Formulation:BCL7C protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85% as determined by SDS-PAGE.

B-cell CLL/lymphoma 7C (BCL7C) is identified by the likeness of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene which is directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of the BCL7C gene has not been determined yet.

BCL7C Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 240 amino acids (1-217 a.a) and having a molecular mass of 25.9kDa (Molecular size on SDS-PAGE will appear higher).BCL7C is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Bcl-7C: May play an anti-apoptotic role. Belongs to the BCL7 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 16p11
UniProt Protein Details:
NCBI Summary:This gene is identified by the similarity of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
UniProt Code:Q8WUZ0
NCBI GenInfo Identifier:296439426
NCBI Gene ID:9274
NCBI Accession:Q8WUZ0.3
UniProt Secondary Accession:Q8WUZ0,O43770, Q6PD89
UniProt Related Accession:Q8WUZ0
Molecular Weight:26,422 Da
NCBI Full Name:B-cell CLL/lymphoma 7 protein family member C
NCBI Synonym Full Names:BCL tumor suppressor 7C
NCBI Official Symbol:BCL7C��
NCBI Official Synonym Symbols:
NCBI Protein Information:B-cell CLL/lymphoma 7 protein family member C
UniProt Protein Name:B-cell CLL/lymphoma 7 protein family member C
UniProt Synonym Protein Names:
Protein Family:B-cell CLL/lymphoma 7 protein family
UniProt Gene Name:BCL7C��
UniProt Entry Name:BCL7C_HUMAN

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