Human BAFF-R Recombinant Protein (hFc Tag) (HDPT0107)
- SKU:
- HDPT0107
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human BAFF-R Recombinant Protein (hFc Tag)
| Description: | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. |
| Product name: | Human BAFF-R Recombinant Protein (hFc Tag) |
| Synonyms: | BAFFR,TNFRSF13C,BAFF-R,BROMIX,CD268,CVID4,prolixin |
| Type: | protein |
| Size: | 50 µg |
| Name: | BAFF-R |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | BAFF-R（Ser7-Ala71）+hFc（Glu99-Ala330） |
| Gene ID: | 115650 |
| Uniprot: | Q96RJ3 |
| Molecular Weight: | 32.7 kDa |
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