Human B7-2 Recombinant Protein (mFc-His Tag) (HDPT0034)
- SKU:
- HDPT0034
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human B7-2 Recombinant Protein (mFc-His Tag)
Description: | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
Product name: | Human B7-2 Recombinant Protein (mFc-His Tag) |
Synonyms: | CD86, B7-2, B70, CD28LG2, LAB72, MGC34413 |
Type: | protein |
Size: | 50 µg |
Name: | B7-2 |
Origin: | Human |
Source: | HEK293 |
Protein Type: | Recombinant |
Application: | Contact Technical Support |
Purity: | > 95% |
Purification: | affinity purification |
Format: | Lyophilized |
Conjugate: | C-Mouse Fc and 6×His tag |
Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
Usage: | Research use only |
Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
Reconstitution: | Reconstitute with deionized water |
Sequence: | B7-2(Leu26-Pro247)+mFc(Pro99-Lys330)+6×His tag |
Gene ID: | 942 |
Uniprot: | P42081 |
Molecular Weight: | 52.4 kDa |