Human ART4 Recombinant Protein (RPPB1415)
- SKU:
- RPPB1415
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q93070
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human ART4 Recombinant Protein |
| Product Code: | RPPB1415 |
| Size: | 5µg |
| Species: | Human |
| Target: | ART4 |
| Synonyms: | ARTC4, DOK1, CD297 Antigen, Dombrock Blood Group, ADP-Ribosyltransferase 4, Ecto-ADP-Ribosyltransferase 4. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | ART4 protein solution (0.25mg/ml) contains Buffered Saline (pH 7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADPSEVAIKI DFDFAPGSFD DQYQGCSKQV MEKLTQGDYF TKDIEAQKNY FRMWQKAHLA WLNQGKVLPQ NMTTTHAVAI LFYTLNSNVH SDFTRAMASV ARTPQQYERS FHFKYLHYYL TSAIQLLRKD SIMENGTLCY EVHYRTKDVH FNAYTGATIR FGQFLSTSLL KEEAQEFGNQ TLFTIFTCLG APVQYFSLKK EVLIPPYELF KVINMSYHPR GDWLQLRSTG NLSTYNCQLL KAHHHHHH |
Ecto-ADP-Ribosyltransferase 4 or ART4 is typed as a glycosylphosphatidylinositol (GPI)-linked membrane protein which carries Dombrock blood group antigens. The development of this protein takes place at the highest levels in the fetal liver. �the process of the ART4 development is regulated while the erythroid differentiation process occurs. ART4 is a is part of the Ribosyltransferase family.
ART4 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 248 amino acids (47-285 a.a.) and having a molecular mass of 28.8kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). ART4 is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
| NCBI Summary: | This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q93070 |
| NCBI GenInfo Identifier: | 22261809 |
| NCBI Gene ID: | 420 |
| NCBI Accession: | Q93070.2 |
| UniProt Related Accession: | Q93070 |
| Molecular Weight: | 36kDa |
| NCBI Full Name: | Ecto-ADP-ribosyltransferase 4 |
| NCBI Synonym Full Names: | ADP-ribosyltransferase 4 (Dombrock blood group) |
| NCBI Official Symbol: | ART4�� |
| NCBI Official Synonym Symbols: | DO; DOK1; ARTC4; CD297; DO/ART4�� |
| NCBI Protein Information: | ecto-ADP-ribosyltransferase 4 |
| UniProt Protein Name: | Ecto-ADP-ribosyltransferase 4 |
| UniProt Synonym Protein Names: | ADP-ribosyltransferase C2 and C3 toxin-like 4; ARTC4; Dombrock blood group carrier molecule; Mono(ADP-ribosyl)transferase 4; NAD(P)(+)--arginine ADP-ribosyltransferase 4; CD_antigen: CD297 |
| Protein Family: | Ecto-ADP-ribosyltransferase |
| UniProt Gene Name: | ART4�� |
