Human APOM Recombinant Protein (RPPB0063)
- SKU:
- RPPB0063
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O95445
- Research Area:
- Cytokines
Description
| Product Name: | Human APOM Recombinant Protein |
| Product Code: | RPPB0063 |
| Size: | 10µg |
| Species: | Human |
| Target: | APOM |
| Synonyms: | G3a, HSPC336, NG20, Apolipoprotein M, APOM, Apo-M, MGC22400. |
| Source: | HEK293 Cells |
| Physical Appearance: | White lyophilized (freeze-dried) powder. |
| Formulation: | APOM Human was filtered (0.4�m) and lyophilized from 0.5 mg/ml supplied in 20mM TRIS and 50mM NaCl, pH 7.5. |
| Solubility: | It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture. |
| Stability: | Store lyophilized APOM Human at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted APOM Human can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | HVDYKDDDDK PAGCPEHSQL TTLGVDGKEF PEVHLGQWYF IAGAAPTKEE LATFDPVDNI VFNMAAGSAP MQLHLRATIR MKDGLCVPRK WIYHLTEGST DLRTEGRPDM KTELFSSSCP GGIMLNETGQ GYQRFLLYNR SPHPPEKCVE EFKSLTSCLD SKAFLLTPRN QEACELSNN |
APOM is belongs to the lipocalin protein family and is associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. APOM is secreted through the plasma membrane but remains membrane-bound, where it takes part in lipid transport.
APOM HEK Human Recombinant Protein is 20 kDa protein containing 179 amino acid residues of the APOM Human and 13 additional amino acid residues of flag Tag.
| UniProt Protein Function: | APOM: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. Plasma protein. Expressed in liver and kidney. Belongs to the calycin superfamily. Lipocalin family. Highly divergent. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 6p21.33 Cellular Component: integral to plasma membrane Molecular Function:antioxidant activity; lipid transporter activity; phospholipid binding Biological Process: cholesterol homeostasis; reverse cholesterol transport; response to glucose stimulus; cholesterol efflux; lipoprotein metabolic process |
| NCBI Summary: | The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012] |
| UniProt Code: | O95445 |
| NCBI GenInfo Identifier: | 17370872 |
| NCBI Gene ID: | 55937 |
| NCBI Accession: | O95445.2 |
| UniProt Secondary Accession: | O95445,Q5SRP4, Q9P046, Q9UMP6, B0UX98, |
| UniProt Related Accession: | O95445 |
| Molecular Weight: | 188 |
| NCBI Full Name: | Apolipoprotein M |
| NCBI Synonym Full Names: | apolipoprotein M |
| NCBI Official Symbol: | APOM�� |
| NCBI Official Synonym Symbols: | G3a; NG20; apo-M; HSPC336�� |
| NCBI Protein Information: | apolipoprotein M; protein G3a; NG20-like protein; alternative name: G3a, NG20 |
| UniProt Protein Name: | Apolipoprotein M |
| UniProt Synonym Protein Names: | Protein G3a |
| Protein Family: | Apomucin |
| UniProt Gene Name: | APOM�� |
| UniProt Entry Name: | APOM_HUMAN |
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