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Human APLNR Full-Length Bioactive Membrane Protein (HDFP113)

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SKU:
HDFP113
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P35414
$1,667

Description

system_update_altDatasheet
Product nameHuman APLNR full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP113
Product CategoryFull Length Transmembrane Proteins
Target:APLNR
Uniprot:P35414
Description:Human APLNR full length protein-synthetic nanodisc
Molecular Weight:The human full length APLNR protein has a MW of 42.7 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:Neuroactive ligand-receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:AGTRL1; APJ; APJR; HG11
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]
Delivery:3-4 weeks
UsageResearch use only

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