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Human AP1M1 / AP-1 complex subunit mu-1 ELISA Kit

SKU:
HUFI01141
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9BXS5
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Competitive
Synonyms:
AP1M1, AP-1 complex subunit mu-1, Clathrin coat-associated protein AP47, Clathrin coat assembly protein AP47, Clathrin assembly protein complex 1 medium chain 1, Adaptor-related protein complex 1 mu-1 subunit, Mu1A-adaptin, Mu-adaptin 1, AP-mu chain
Reactivity:
Human
Research Area:
Immunology
€599
Frequently bought together:

Description

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Human AP1M1 / AP-1 complex subunit mu-1 ELISA Kit

The medium chain of the trans-Golgi network clathrin-associated protein complex AP-1 is encoded by AP1M1/AP-1 complex subunit mu-1. Beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1 are the other components of this complex. This complex connects clathrin to receptors in coated vesicles and is found at the Golgi vesicle. Endocytosis and Golgi processing are both aided by these vesicles. Mental Retardation, Enteropathy, Deafness, Peripheral Neuropathy, Ichthyosis, Keratoderma, and Pettigrew Syndrome are all diseases linked to AP1M1. Pathways associated tp AP1M1/AP-1 complex subunit beta include HIV Life Cycle and Nef-mediated down modulation of cell surface receptors by recruiting them to clathrin adapters. AP1M2 is a significant paralog of this gene.