null

Human AMTN Recombinant Protein (RPPB2734)

SKU:
RPPB2734
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q6UX39
€309
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human AMTN Recombinant Protein
Product Code:RPPB2734
Size:20µg
Species:Human
Target:AMTN
Synonyms:UNQ689, Amelotin, PRO1329.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:AMTN protein solution (0.5mg/ml) contains mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 20% glycerol and 2mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSLPQLKPA LGLPPTKLAP DQGTLPNQQQ SNQVFPSLSL IPLTQMLTLG PDLHLLNPAA GMTPGTQTHP LTLGGLNVQQ QLHPHVLPIF VTQLGAQGTI LSSEELPQIF TSLIIHSLFP GGILPTSQAG ANPDVQDGSL PAGGAGVNPA TQGTPAGRLP TPSGTDDDFA VTTPAGIQRS THAIEEATTE SANGIQ

AMTN is a member of the amelotin family. AMTN is a lately discovered secreted enamel protein. AMTN mainly expressed during the maturation stage of enamel formation. AMTN gathers in a basal lamina-like structure at the interface between ameloblasts and enamel mineral and it co-localizes with one more lately described enamel protein, odontogenic ameloblast- related protein (ODAM(.

AMTN Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 216 amino acids (17-209 a.a.) and having a molecular mass of 22.2kDa.AMTN is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:AMTN: Could be a cell adhesion protein involved in the maturation of tooth enamel. Belongs to the amelotin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Extracellular matrix; Secreted; Secreted, signal peptide; Cell adhesionChromosomal Location of Human Ortholog: 4q13.3Cellular Component: basal lamina; intercellular junction; proteinaceous extracellular matrixBiological Process: odontogenesis of dentine-containing teeth
UniProt Protein Details:
NCBI Summary:The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM, Mar 2008]
UniProt Code:Q6UX39
NCBI GenInfo Identifier:55976710
NCBI Gene ID:401138
NCBI Accession:Q6UX39.1
UniProt Secondary Accession:Q6UX39,Q0P503, Q0P506
UniProt Related Accession:Q6UX39
Molecular Weight:21,459 Da
NCBI Full Name:Amelotin
NCBI Synonym Full Names:amelotin
NCBI Official Symbol:AMTN��
NCBI Official Synonym Symbols:UNQ689��
NCBI Protein Information:amelotin
UniProt Protein Name:Amelotin
UniProt Synonym Protein Names:
Protein Family:Amelotin
UniProt Gene Name:AMTN��
UniProt Entry Name:AMTN_HUMAN

Related Products