Human AMIGO2 Recombinant Protein (RPPB2731)
- SKU:
- RPPB2731
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q86SJ2
Description
| Product Name: | Human AMIGO2 Recombinant Protein |
| Product Code: | RPPB2731 |
| Size: | 10µg |
| Species: | Human |
| Target: | AMIGO2 |
| Synonyms: | AdhesionMolecule with Ig-Like Domain 2, Differentially Expressed in Gastric, Adenocarcinomas,AMIGO-2, ALI1, DEGA, Differentially Expressed in Gastric, Adenocarcinoma, Amphoterin-InducedGene and Open Reading Frame 2, Transmembrane Protein AMIGO2, Amphoterin InducedGene, Alivin 1, Alivin-1. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterilefiltered colorless solution. |
| Formulation: | AMIGO2protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greaterthan 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | VCPTACICAT DIVSCTNKNL SKVPGNLFRL IKRLDLSYNR IGLLDSEWIP VSFAKLNTLILRHNNITSIS TGSFSTTPNL KCLDLSSNKL KTVKNAVFQE LKVLEVLLLY NNHISYLDPS AFGGLSQLQK LYLSGNFLTQ FPMDLYVGRF KLAELMFLDV SYNRIPSMPM HHINLVPGKQ LRGIYLHGNP FVCDCSLYSL LVFWYRRHFS SVMDFKNDYT CRLWSDSRHS RQVLLLQDSF�MNCSDSIING SFRALGFIHE AQVGERLMVH CDSKTGNANT DFIWVGPDNR LLEPDKEMEN FYVFHNGSLV IESPRFEDAG VYSCIAMNKQ RLLNETVDVT INVSNFTVSR SHAHEAFNTL�EHHHHHH |
Adhesion Molecule with Ig-Like Domain 2, also known as AMIGO2 is a memberof the leucine-rich repeat family. AMIGO2 arbitrates homophilic in addition toheterophilic cell-cell interaction with AMIGO1 or AMIGO3. Furthermore, AMIGO2 contributes to signal transduction via its intracellular domain and isalso essential for tumorigenesis of a subset of gastric adenocarcinomas.
AMIGO2 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 367 amino acids (40-398a.a.) and having a molecular mass of 41.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa).AMIGO2 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86SJ2 |
| NCBI GenInfo Identifier: | 219521831 |
| NCBI Gene ID: | 347902 |
| NCBI Accession: | NP_001137140.1 |
| UniProt Secondary Accession: | Q86SJ2,Q4VBP6, Q7Z4A0, Q96CN8 |
| UniProt Related Accession: | Q86SJ2 |
| Molecular Weight: | 57 |
| NCBI Full Name: | amphoterin-induced protein 2 |
| NCBI Synonym Full Names: | adhesion molecule with Ig like domain 2 |
| NCBI Official Symbol: | AMIGO2�� |
| NCBI Official Synonym Symbols: | ALI1; DEGA; AMIGO-2�� |
| NCBI Protein Information: | amphoterin-induced protein 2 |
| UniProt Protein Name: | Amphoterin-induced protein 2 |
| UniProt Synonym Protein Names: | AMIGO-2; Alivin-1; Differentially expressed in gastric adenocarcinomas; DEGA |
| Protein Family: | |
| UniProt Gene Name: | AMIGO2�� |
| UniProt Entry Name: |
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