The Human Albumin Polyclonal Antibody is a valuable tool for research involving human albumin, a key protein found in the blood that plays a critical role in maintaining osmotic pressure and transporting various molecules throughout the body. This antibody is specifically designed to target human albumin and is raised in rabbits, ensuring high reactivity and specificity in detecting the protein in various samples.Validated for use in Western blot applications, the Human Albumin Polyclonal Antibody is ideal for studying albumin expression and function in different cell types and tissues. Its ability to bind specifically to human albumin enables accurate detection and analysis, making it a valuable asset for researchers in fields such as biochemistry, pharmacology, and medicine.
The importance of human albumin in various physiological processes, including maintaining fluid balance, binding and transporting hormones and drugs, and modulating immune responses, underscores the significance of studying this protein in both health and disease. Research using the Human Albumin Polyclonal Antibody can provide insights into the role of albumin in conditions such as liver disease, kidney dysfunction, and cardiovascular disorders, leading to potential therapeutic developments and diagnostic strategies.
Product Name:
Human albumin Polyclonal Antibody
SKU:
CAB24843
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-609 of human albumin(NP_000468.1).
ALB; HSA; PRO0883; PRO0903; PRO1341; albumin; Human albumin
Positive Sample:
Mouse liver
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
45kDa/47kDa/69kDa
Observed MW:
69kDa
Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.
Purification Method:
Affinity purification
Gene ID:
213
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver using Human albumin Rabbit pAb(CAB24843) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:20s.
_IF_01__22291.1701347401.jpg?c=2&imbypass=on "Immunofluorescence analysis of Hep G2 cells using Human albumin Rabbit pAb (CAB24843) at dilution of 1:200 (40x lens). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (AS007) at 1:500 dilution. Blue: DAPI for nuclear staining.")
