null

Human ADRB3 full length protein-synthetic nanodisc (HDFP181)

SKU:
HDFP181
Size:
10μg
Target:
ADRB3
Tag:
C-Flag Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,389
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Nanodisc Human ADRB3 Protein
SKU:HDFP181
Size:10μg
Target:ADRB3
Tag:C-Flag Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:BETA3AR
Protein Families:GPCR, Transmembrane, Druggable Genome.
Protein Description:Human ADRB3 full length protein-synthetic nanodisc
Protein Pathways:Calcium regulation in cardiac cells, GPCRDB Class A Rhodopsin-like, Monoamine GPCRs, Cancer, Metabolic and Obesity, Insulin Signaling Pathway.
Molecular Weight:The human full length ADRB3 protein has a MW of 43.5kDa

The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]

Uniprot ID:P13945
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

Related Products