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Human ADRB1-Strep full length protein-synthetic nanodisc (HDFP1221)

SKU:
HDFP1221
Size:
10μg
Target:
ADRB1
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249
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Description

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Product Name:Nanodisc Human ADRB1-Strep Protein
SKU:HDFP1221
Size:10μg
Target:ADRB1
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:ADRB1R; B1AR; BETA1AR; FNSS2; RHR
Protein Families:Druggable Genome, GPCR, Transmembrane.
Protein Description:Human ADRB1-Strep full length protein-synthetic nanodisc
Protein Pathways:Calcium signaling pathway, Dilated cardiomyopathy, Endocytosis, Gap junction, Neuroactive ligand-receptor interaction.
Molecular Weight:The human full length ADRB1-Strep protein has a MW of 51.2 kDa

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.

Uniprot ID:P08588
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

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