Nanodisc Human ADGRG1-Strep Protein (HDFP840)
- SKU:
- HDFP840
- Size:
- 10μg
- Target:
- ADGRG1
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
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Description
| Product Name: | Nanodisc Human ADGRG1-Strep Protein |
| SKU: | HDFP840 |
| Size: | 10μg |
| Target: | ADGRG1 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | BFPP; BPPR; GPR56; TM7LN4; TM7XN1 |
| Protein Families: | Druggable Genome, GPCR, Transmembrane. |
| Protein Description: | Human ADGRG1-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | N.A. |
| Molecular Weight: | The human full length ADGRG1-Strep protein has a MW of 77.7 kDa |
A member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria.
| Uniprot ID: | Q9Y653 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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