Human ADAT1 Recombinant Protein (RPPB5789)
- SKU:
- RPPB5789
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BUB4
- Research Area:
- Enzymes
Frequently bought together:
Description
Product Name: | Human ADAT1 Recombinant Protein |
Product Code: | RPPB5789 |
Size: | 10µg |
Species: | Human |
Target: | ADAT1 |
Synonyms: | tRNA-specific adenosine deaminase 1, hADAT1, tRNA-specific adenosine- 37 deaminase, ADAT1, ADAT-1. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile Filtered clear solution. |
Formulation: | Adenosine Deaminase tRNA-Specific-1 at 0.1mg/ml, 10mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Purity: | Greater than 95.0% as determined by SDS-PAGE. |
This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA.
Adenosine Deaminase tRNA-Specific 1 Human Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing amino acids 1-502 and having a total molecular mass of 57.7 kda. ADAT-1 contains T7 tag at N-terminus. ADAT1 is purified by proprietary chromatographic techniques.
UniProt Protein Function: | ADAT1: Specifically deaminates adenosine-37 to inosine in tRNA- Ala. Belongs to the ADAT1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA processing; EC 3.5.4.34; HydrolaseChromosomal Location of Human Ortholog: 16q23.1Molecular Function: RNA binding; tRNA-specific adenosine deaminase activityBiological Process: tRNA processing |
UniProt Protein Details: | |
NCBI Summary: | This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] |
UniProt Code: | Q9BUB4 |
NCBI GenInfo Identifier: | 74733201 |
NCBI Gene ID: | 23536 |
NCBI Accession: | Q9BUB4.1 |
UniProt Secondary Accession: | Q9BUB4,Q9NVB7, Q9UNG3 |
UniProt Related Accession: | Q9BUB4 |
Molecular Weight: | 38,706 Da |
NCBI Full Name: | tRNA-specific adenosine deaminase 1 |
NCBI Synonym Full Names: | adenosine deaminase, tRNA specific 1 |
NCBI Official Symbol: | ADAT1�� |
NCBI Official Synonym Symbols: | HADAT1�� |
NCBI Protein Information: | tRNA-specific adenosine deaminase 1 |
UniProt Protein Name: | tRNA-specific adenosine deaminase 1 |
UniProt Synonym Protein Names: | tRNA-specific adenosine-37 deaminase |
Protein Family: | tRNA-specific adenosine deaminase |
UniProt Gene Name: | ADAT1�� |
UniProt Entry Name: | ADAT1_HUMAN |