null

Human ADA1A-Strep full length protein-synthetic nanodisc (HDFP912)

SKU:
HDFP912
Size:
10μg
Target:
ADA1A
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Nanodisc Human ADA1A-Strep Protein
SKU:HDFP912
Size:10μg
Target:ADA1A
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:ADRA1C, ADRA1L1, ALPHA1AAR
Protein Families:GPCR, Transmembrane, Druggable Genome.
Protein Description:Human ADA1A-Strep full length protein-synthetic nanodisc
Protein Pathways:Calcium regulation in cardiac cells, GPCRDB Class A Rhodopsin-like, Monoamine GPCRs, Apoptosis, Cancer, Cell Cycle.
Molecular Weight:The human full length ADA1A-Strep protein has a MW of 51.5 kDa

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]

Uniprot ID:P35348
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

Related Products