Human ADA1A full length protein-synthetic nanodisc (HDFP174)
- SKU:
- HDFP174
- Size:
- 10μg
- Target:
- ADA1A
- Tag:
- C-Flag Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
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Description
| Product Name: | Nanodisc Human ADA1A Protein |
| SKU: | HDFP174 |
| Size: | 10μg |
| Target: | ADA1A |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | ADRA1C, ADRA1L1, ALPHA1AAR |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human ADA1A full length protein-synthetic nanodisc |
| Protein Pathways: | Calcium regulation in cardiac cells, GPCRDB Class A Rhodopsin-like, Monoamine GPCRs, Apoptosis, Cancer, Cell Cycle. |
| Molecular Weight: | The human full length ADA1A protein has a MW of 51.5kDa |
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
| Uniprot ID: | P35348 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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