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Human ACTHR-Strep full length protein-synthetic nanodisc (HDFP911)

SKU:
HDFP911
Size:
10μg
Target:
ACTHR
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Nanodisc Human ACTHR-Strep Protein
SKU:HDFP911
Size:10μg
Target:ACTHR
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:ACTHR
Protein Families:GPCR, Transmembrane, Druggable Genome.
Protein Description:Human ACTHR-Strep full length protein-synthetic nanodisc
Protein Pathways:GPCRDB Class A Rhodopsin-like, Peptide GPCRs.
Molecular Weight:The human full length ACTHR-Strep protein has a MW of 33.9 kDa

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014]

Uniprot ID:Q01718
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

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