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Human ACKR4-Strep full length protein-synthetic nanodisc (HDFP906)

SKU:
HDFP906
Size:
10μg
Target:
ACKR4
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249

Description

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Product Name:Nanodisc Human ACKR4-Strep Protein
SKU:HDFP906
Size:10μg
Target:ACKR4
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:CC-CKR-11, CCBP2, CCR-11, CCR10, CCR11, CCRL1, CCX CKR, CCX-CKR, CKR-11, PPR1, VSHK1
Protein Families:GPCR, Transmembrane, Druggable Genome.
Protein Description:Human ACKR4-Strep full length protein-synthetic nanodisc
Protein Pathways:GPCRDB Class A Rhodopsin-like, Chemokines, Chemokine and Receptor.
Molecular Weight:The human full length ACKR4-Strep protein has a MW of 39.9 kDa

The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013]

Uniprot ID:Q9NPB9
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

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