Description
Product Name: | Nanodisc Human ACHA6-Strep Protein |
SKU: | HDFP1412 |
Size: | 10μg |
Target: | ACHA6 |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | CHNRA6 |
Protein Families: | Ion Channels: Cys-loop Receptors. |
Protein Description: | Human ACHA6-Strep full length protein-synthetic nanodisc |
Molecular Weight: | The human full length ACHA6-Strep protein has a MW of 56.9 kDa |
This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010]
Uniprot ID: | Q15825 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |