Human AAGAB Recombinant Protein (RPPB2691)
- SKU:
- RPPB2691
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q6PD74
Frequently bought together:
Description
| Product Name: | Human AAGAB Recombinant Protein |
| Product Code: | RPPB2691 |
| Size: | 20µg |
| Species: | Human |
| Target: | AAGAB |
| Synonyms: | P34, Alpha- and gamma-adaptin-binding protein p34. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | AAGAB protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MAAGVPCALV TSCSSVFSGD QLVQHILGTE DLIVEVTSND AVRFYPWTID NKYYSADINL CVVPNKFLVT AEIAESVQAF VVYFDSTQKS GLDSVSSWLP LAKAWLPEVM ILVCDRVSED GINRQKAQEW CIKHGFELVE LSPEELPEED DDFPESTGVK RIVQALNANV WSNVVMKNDR NQGFSLLNSL TGTNHSIGSA DPCHPEQPHL PAADSTESLS DHRGGASNTT DAQVDSIVDP MLDLDIQELA SLTTGGGDVE NFERLFSKLK EMKDKAATLP HEQRKVHAEK VAKAFWMAIG GDRDEIEGLS SDEEH |
Alpha & Gamma-Adaptin Binding Protein (AAGAB), which is also known as P34, takes part in membrane traffic and interacts with AP1G1 and AP2A1.AAGAB is highly expressed in skin and keratinocytes, with the highest levels in adrenal gland, rectum and thymus.
AAGAB Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 335 amino acids (1-315 a.a.) and having a molecular mass of 36.7kDa.AAGAB is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | May be involved in endocytic recycling of growth factor receptors such as EGFR. |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q6PD74 |
| NCBI GenInfo Identifier: | 153251315 |
| NCBI Gene ID: | 79719 |
| NCBI Accession: | NP_078942 |
| UniProt Secondary Accession: | Q6PD74,Q6FI86, Q7Z5X9, Q9H0P1, Q9HAK0, B4DG44 |
| UniProt Related Accession: | Q6PD74 |
| Molecular Weight: | 36.7kDa (335aa), confirmed by MALDI-TOF |
| NCBI Full Name: | alpha- and gamma-adaptin-binding protein p34 isoform 1 |
| NCBI Synonym Full Names: | alpha and gamma adaptin binding protein |
| NCBI Official Symbol: | AAGAB�� |
| NCBI Official Synonym Symbols: | p34; KPPP1; PPKP1; PPKP1A�� |
| NCBI Protein Information: | alpha- and gamma-adaptin-binding protein p34 |
| UniProt Protein Name: | Alpha- and gamma-adaptin-binding protein p34 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Alpha- and gamma-adaptin-binding protein |
| UniProt Gene Name: | AAGAB�� |
| UniProt Entry Name: |
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