Human 5HT3A full length protein-synthetic nanodisc (HDFP687)
- SKU:
- HDFP687
- Size:
- 10μg
- Target:
- 5HT3A
- Tag:
- C-Flag Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
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Description
| Product Name: | Nanodisc Human 5HT3A Protein |
| SKU: | HDFP687 |
| Size: | 10μg |
| Target: | 5HT3A |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3 |
| Protein Families: | Ion Channels: Cys-loop Receptors. |
| Protein Description: | Human 5HT3A full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length 5HT3A protein has a MW of 55.3kDa |
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
| Uniprot ID: | P46098 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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