Human 4-1BB Recombinant Protein (mFc-His Tag) (HDPT0011)
- SKU:
- HDPT0011
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human 4-1BB Recombinant Protein (mFc-His Tag)
| Description: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |
| Product name: | Human 4-1BB Recombinant Protein (mFc-His Tag) |
| Synonyms: | TNFRSF9, 4-1BB, CD137, CDw137, ILA |
| Type: | protein |
| Size: | 50 µg |
| Name: | 4-1BB |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Flow Cyt |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Mouse Fc and 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | 41BB（Leu24-Gln186）+mFc（Pro99-Lys330）+6×His |
| Gene ID: | 3604 |
| Uniprot: | Q07011 |
| Molecular Weight: | 54-60 kDa |
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