The HTRA3 Polyclonal Antibody (CAB14649) is a valuable tool for researchers studying HTRA3, a member of the high temperature requirement A (HtrA) protease family. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various research applications, including Western blotting. By binding to the HTRA3 protein, this antibody enables accurate detection and analysis in different cell types, making it an essential asset for studies in protease biology and cancer research.
HTRA3 plays a crucial role in cellular homeostasis by regulating proteolytic processes and maintaining protein quality control. Dysregulation of HTRA3 has been linked to various pathologies, including cancer and neurodegenerative diseases, making it a promising target for therapeutic intervention. Investigating the biological function of HTRA3 is essential for elucidating its role in disease development and identifying potential treatment strategies aimed at modulating its activity.
Product Name:
HTRA3 Rabbit Polyclonal Antibody
SKU:
CAB14649
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 334-453 of human HTRA3 (NP_444272.1).
Enables endopeptidase activity; identical protein binding activity; and serine-type peptidase activity. Involved in proteolysis. Predicted to be located in extracellular region.
Purification Method:
Affinity purification
Gene ID:
94031
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HTRA3 antibody (CAB14649) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
