HTRA2 Rabbit Polyclonal Antibody (CAB14877)
- SKU:
- CAB14877
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | HTRA2 Rabbit Polyclonal Antibody |
SKU: | CAB14877 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 334-458 of human HTRA2 (NP_037379.1). |
Sequence: | PSDR LREF LHRG EKKN SSSG ISGS QRRY IGVM MLTL SPSI LAEL QLRE PSFP DVQH GVLI HKVI LGSP AHRA GLRP GDVI LAIG EQMV QNAE DVYE AVRT QSQL AVQI RRGR ETLT LYVT PEVT E |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | OMI; MGCA8; PARK13; PRSS25; HTRA2 |
Positive Sample: | MCF7 |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion intermembrane space, Mitochondrion membrane, Single-pass membrane protein. |
Calculated MW: | 49kDa |
Observed MW: | 36kDa |
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 27429 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |