The HTR5B Polyclonal Antibody (PACO02280) is a valuable tool for researchers studying the serotonin receptor 5B (HTR5B). This antibody, raised in rabbits, is highly specific to HTR5B and is validated for use in various applications, including Western blotting and immunohistochemistry.HTR5B is a key player in the serotonin signaling pathway and is involved in various physiological processes, including mood regulation and cognitive function. Dysregulation of HTR5B has been implicated in several neuropsychiatric disorders, making it a promising target for therapeutic interventions.
By using the HTR5B Polyclonal Antibody, researchers can accurately detect and analyze HTR5B expression in different cell types and tissues, providing valuable insights into its function and potential role in disease pathology. This antibody is an essential tool for studies in neuroscience, pharmacology, and drug development aimed at targeting the serotonin system for therapeutic purposes.
Antibody Name:
HTR5B Antibody
Antibody SKU:
PACO02280
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Mouse, Rat
Immunogen:
synthesized peptide derived from the C-terminal region of human SR-5B.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
5-hydroxytryptamine receptor 5B
UniProt Protein Function:
5-HT(5B): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. Probably involved in anxiety and depression. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Receptor, GPCRCellular Component: integral to membrane; integral to plasma membrane; membrane; plasma membraneMolecular Function: drug binding; G-protein coupled receptor activity; serotonin binding; serotonin receptor activity; signal transducer activityBiological Process: G-protein coupled receptor protein signaling pathway; serotonin receptor signaling pathway; signal transduction
