The HTR3E Antibody (Biotin Conjugated) is a valuable tool for researchers investigating the function of the HTR3E gene, which codes for the 5-hydroxytryptamine receptor 3E involved in serotonin signaling. This antibody, conjugated with biotin for enhanced detection, is raised in rabbits and highly specific for human samples, making it an excellent choice for studies in neuroscience and pharmacology.The HTR3E Antibody binds specifically to the HTR3E protein, allowing for precise detection and analysis in various cell types and tissues. Its reactivity with human samples and validation for use in Western blot applications ensure accurate and reliable results in research focused on serotonin receptor function and its role in neurological disorders and mental health conditions.
Understanding the function and regulation of the HTR3E receptor is essential for advancing the development of targeted therapies for conditions such as anxiety, depression, and nausea, where serotonin signaling plays a crucial role. The HTR3E Antibody provides researchers with a powerful tool to investigate the mechanisms underlying these disorders and explore new treatment options.
Antibody Name:
HTR3E Antibody?Biotin conjugated (PACO64086)
Antibody SKU:
PACO64086
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human 5-hydroxytryptamine receptor 3E protein (26-248AA)
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
Synonyms:
5-hydroxytryptamine receptor 3E (5-HT3-E) (5-HT3E) (Serotonin receptor 3E), HTR3E
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This locus encodes a 5-hydroxytryptamine (serotonin) receptor subunit. The encoded protein, subunit E, may play a role in neurotransmission in myenteric neurons. Genes encoding subunits C, D and E form a cluster on chromosome 3. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2012]
