The HTR3C Polyclonal Antibody (PAC015797) is a valuable tool for researchers studying the HTR3C gene, which encodes a subunit of the 5-HT3 receptor, a ligand-gated ion channel involved in serotonin signaling. This rabbit-derived antibody exhibits high specificity and sensitivity for human samples and is suitable for use in Western blot applications.The HTR3C antibody binds specifically to the HTR3C protein, enabling precise detection and analysis in a variety of cell types. Its application in research extends to studies in neurobiology, psychiatry, and pharmacology, where the 5-HT3 receptor plays a crucial role in modulating neurotransmission and behavior.
By utilizing the HTR3C Polyclonal Antibody, researchers can delve deeper into the functions and regulation of the 5-HT3 receptor, shedding light on its involvement in various physiological and pathological processes. This antibody serves as a valuable tool for investigating the role of HTR3C in serotonin signaling and its potential implications for drug development and therapeutic interventions in disorders related to serotonin dysfunction.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15797(HTR3C Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HT29 cells, Primary antibody: PACO15797(HTR3C Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO15797(HTR3C Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008]
