HTR3A Rabbit Polyclonal Antibody (CAB5647)
- SKU:
- CAB5647
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | HTR3A Rabbit Polyclonal Antibody |
SKU: | CAB5647 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-241 of human HTR3A (NP_000860.2). |
Sequence: | LAQG EARR SRNT TRPA LLRL SDYL LTNY RKGV RPVR DWRK PTTV SIDV IVYA ILNV DEKN QVLT TYIW YRQY WTDE FLQW NPED FDNI TKLS IPTD SIWV PDIL INEF VDVG KSPN IPYV YIRH QGEV QNYK PLQV VTAC SLDI YNFP FDVQ NCSL TFTS WLHT IQDI NISL WRLP EKVK SDRS VFMN QGEW ELLG VLPY FREF SMES SNYY AEMK FY |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R; HTR3A |
Positive Sample: | HepG2,Mouse brain,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse. |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 3359 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |