In a similar fashion, the HTR1E Antibody (PAC01534) offered by Assay Genie is a valuable tool for researchers studying the serotonin receptor subtype 1E (HTR1E). This polyclonal antibody is specifically designed for use in Western blot applications and has been raised in rabbits for high reactivity with human samples.HTR1E is a G protein-coupled receptor that plays a role in modulating serotonin levels in the brain, making it a key target for research in neuropsychiatric disorders such as depression, anxiety, and schizophrenia. By binding to the HTR1E protein, this antibody enables researchers to detect and analyze its expression in various cell types, providing valuable insights into its function and potential therapeutic applications.
Overall, the HTR1E Antibody from Assay Genie is a reliable tool for researchers looking to delve deeper into the mechanisms of serotonin signaling and its implications for mental health disorders. Its specificity and reactivity make it an essential component for studies in neuroscience, pharmacology, and drug development.
Antibody Name:
HTR1E Antibody
Antibody SKU:
PACO01534
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human SR-1E.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
HTR1E; 5-hydroxytryptamine receptor 1E; 5-HT-1E; 5-HT1E; S31; Serotonin receptor 1E
UniProt Protein Function:
5-HT(1E): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-passChromosomal Location of Human Ortholog: 6q14-q15Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; protein binding; serotonin binding; serotonin receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cyclic nucleotide second messenger