HTR1B Rabbit Polyclonal Antibody (CAB18285)
- SKU:
- CAB18285
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HTR1B Rabbit Polyclonal Antibody |
SKU: | CAB18285 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-390 of human HTR1B (P28222). |
Sequence: | MEEP GAQC APPP PAGS ETWV PQAN LSSA PSQN CSAK DYIY QDSI SLPW KVLL VMLL ALIT LATT LSNA FVIA TVYR TRKL HTPA NYLI ASLA VTDL LVSI LVMP ISTM YTVT GRWT LGQV VCDF WLSS DITC CTAS ILHL CVIA LDRY WAIT DAVE YSAK RTPK RAAV MIAL VWVF SISI SLPP FFWR QAKA EEEV SECV VNTD HILY TVYS TVGA FYFP TLLL IALY GRIY VEAR SRIL KQTP NRTG KRLT RAQL ITDS PGST SSVT SINS RVPD VPSE SGSP VYVN QVKV RVSD ALLE KKKL MAAR ERKA TKTL GIIL GAFI VCWL PFFI ISLV MPIC KDAC WFHL AIFD FFTW LGYL NSLI NPII YTMS NEDF KQAF HKLI RFKC TS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT-1B; 5-HT1DB; 5-HT-1D-beta; HTR1B |
Positive Sample: | mouse brain,rat brain |
Cellular Localization: | calyx of Held, dendrite, endoplasmic reticulum, plasma membrane, presynaptic membrane, serotonergic synapse |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs.
Purification Method: | Affinity purification |
Gene ID: | 3351 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |