Description
HTLV 1 TAX Monoclonal Antibody [YRHTLV-1tax] (CPAB0393)
The HTLV-1 Tax Antibody (CPAB0393) is a vital tool for researchers studying Human T-cell leukemia virus type 1 (HTLV-1) and its associated oncoprotein Tax. This polyclonal antibody, derived from rabbits, is specifically designed to target the HTLV-1 Tax protein in human samples, making it an ideal choice for Western blot applications.HTLV-1 is a retrovirus that is linked to the development of adult T-cell leukemia/lymphoma and other inflammatory conditions. The Tax protein plays a crucial role in the viral life cycle and is also implicated in the transformation of infected cells.
By detecting and analyzing the HTLV-1 Tax protein, researchers can gain insight into the mechanisms behind HTLV-1-associated diseases and potentially develop targeted therapies.With its high reactivity and specificity for HTLV-1 Tax, the CPAB0393 antibody enables precise detection and analysis of the viral protein in various cell types. This makes it an invaluable tool for studies in virology, oncology, and immunology, providing researchers with the ability to further understand and combat HTLV-1-related disorders.
Product Name: | HTLV 1 TAX antibody |
Product Sku: | CPAB0393 |
Size: | 500μg |
Host Species: | mouse |
Immunogen: | r.HTLV TAX protein |
Clone: | YRHTLV-1tax. |
Reactivity: | Viral |
Applications: | Western Blot, ELISA |
Purification Method: | Ion exchange column. |
Isotype: | IgG2a |
Background: | HTLV-1 is the etiological agent for Adult T-Cell Leukemia which encodes a 40kDa cell-transforming oncoprotein called Tax. HTLV-1 Tax protein sensitizes cells to apoptotic cell death induced by DNA damaging agents. Constitutive Activation of TAK1 by HTLV-1 Tax-dependent Overexpression of TAB2 Induces Activation of JNK-ATF2 but Not IKK-NF-kB. |
Synonyms: | |
Storage Buffer: | In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |