HTATIP2 Monoclonal Antibody [PAT5D6AT] (CPAB0188)
- SKU:
- CPAB0188
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT5D6AT
- Applications:
- WB
- ELISA
- FC
Description
HTATIP2 Monoclonal Antibody [PAT5D6AT] (CPAB0188)
Based on the information from the URL provided (https://www.assaygenie.com/htatip2-antibody-cpab0188/), I can write the following product description:The HTATIP2 Polyclonal Antibody (CPAB0188) is a valuable tool for research involving HTATIP2, a protein known for its role in tumor suppression and regulation of cell growth. This antibody, produced in rabbits, exhibits high specificity for HTATIP2 in human samples and has been validated for use in various applications including Western blotting.HTATIP2, also known as HIV-1 Tat interactive protein 2, is involved in multiple cellular processes including transcriptional regulation and apoptosis.
Research into HTATIP2 has shown its significance in cancer development and progression, making it an attractive target for studying cancer biology and exploring potential therapeutic interventions.By using the HTATIP2 Polyclonal Antibody, researchers can accurately detect and analyze HTATIP2 protein levels in different cell types, providing valuable insights into its molecular mechanisms and potential implications in cancer research. This antibody is a valuable resource for scientists studying HTATIP2 and its role in cellular function and cancer biology.
Product Name: | HTATIP2 Antibody |
Product Sku: | CPAB0188 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human HTATIP2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HTATIP2 amino acids 1-242 purified from Ecoli. |
Clone: | PAT5D6AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA, Flow Cytometry |
Purification Method: | HTATIP2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | HTATIP2 is part of the short-chain dehydrogenases/reductases (SDR) family which acts as a tumor suppressor in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 cooperates with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in HTATIP2 are related with hepatocellular carcinomas and apoptotic resistant tumor cells, implicating a probable use for HTATIP2 in antitumor therapy. |
Synonyms: | TIP30, CC3, SDR44U1, HTATIP2, EC=1.1.1.-, HIV-1 TAT-interactive protein 2, FLJ26963. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |