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HSPH1 Monoclonal Antibody [PJ1G12AT] (CPAB0286)

SKU:
CPAB0286
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PJ1G12AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

HSPH1 Monoclonal Antibody [PJ1G12AT] (CPAB0286)

The HSPH1 Polyclonal Antibody (CPAB0286) is a valuable tool for research involving the HSPH1 protein, a heat shock protein implicated in cellular stress response and protein folding. This antibody, generated in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the HSPH1 protein, researchers can accurately detect and analyze HSPH1 expression in various cell types, making it ideal for studies in cell biology and molecular biology.HSPH1, also known as heat shock protein family H member 1, plays a crucial role in maintaining cellular homeostasis during times of stress.

Its involvement in protein quality control and cellular protection makes it a key player in cell survival and function. Research into the function of HSPH1 is important for understanding cellular stress response mechanisms and developing potential therapeutic strategies for conditions related to protein misfolding and cellular dysfunction. The HSPH1 Polyclonal Antibody is a valuable tool for researchers seeking to explore the role of HSPH1 in health and disease.

Product Name:HSPH1 Antibody
Product Sku:CPAB0286
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HSPH1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSPH1 amino acids 1-858 purified from Ecoli.
Clone:PJ1G12AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:HSPH1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:HSPH1 analysis is used as an indicator and as a diagnostic aid in problematic lesions. HSPH1 chaperones the responses to endoplasmic reticulum (ER) stress during its interactions with GRP78 and GSK3, and without HSP105 cell death following ER stress proceeds by a non-caspase-3-dependent process. HSPH1 is highly expressed in a variety of human tumors. HSPH1 is a mammalian member of the HSP105/110 family, a diverged subgroup of the HSP70 family. HSP105 has 2 isoforms, alpha and beta. Hsp105a associates with Hsp70/Hsc70 as complexes in vivo and regulates the chaperone activity of Hsp70/Hsc70 negatively in vitro and in vivo.
Synonyms:HSPH1, Heat Shock protein 105kDa, 110kDa protein 1, Heat shock 110 kDa protein, HSP110, HSP105α, Antigen NY-CO-25, HSP105, HSP105A, HSP105B, KIAA0201, NY-CO-25, DKFZp686M05240.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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