The HSPD1 Polyclonal Antibody (CAB0969) is a valuable tool for researchers studying heat shock protein HSP60. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the HSPD1 protein, this antibody facilitates the detection and analysis of HSP60 in a variety of cell types.HSP60 is a chaperonin protein that plays a crucial role in the folding and assembly of other proteins within the cell. It is known to be involved in various cellular processes, including protein folding, transport, and signaling.
Dysregulation of HSP60 has been implicated in several diseases, such as neurodegenerative disorders, cancer, and autoimmune conditions.By utilizing the HSPD1 Polyclonal Antibody in their research, scientists can gain further insights into the function and regulation of HSP60 in different physiological and pathological contexts. Understanding the role of HSP60 may lead to the development of novel therapeutic strategies for treating diseases associated with protein misfolding and dysfunction.
Product Name:
HSP60/HSPD1 Rabbit Polyclonal Antibody
SKU:
CAB0969
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-240 of human HSP60/HSPD1 (NP_002147.2).
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Purification Method:
Affinity purification
Gene ID:
3329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using HSP60/HSPD1 Rabbit pAb (CAB0969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
